Gout is an inflammatory disease resulting from deposition of uric acid crystals in tissues and fluids within the body. This process is caused by an overproduction or under-excretion of uric acid. The resulting excess uric acid eventually forms crystals in joints and cause the joints to become inflamed. The joints that are commonly affected include toes (especially the big toe), ankles, knees, and fingers. Acute gout will typically manifest itself as an acutely red, hot, tender and swollen joint with excruciating pain. Recurrent bouts of acute gout can lead to a degenerative form of chronic arthritis called gouty arthritis.